Article

Integrative Single-cell RNA-Seq and ATAC-Seq Analysis of Human Developmental Haematopoiesis

2020-05-07

Abstract excerpt

Regulation of haematopoiesis during human development remains poorly defined. Here, we applied single-cell (sc)RNA-Seq and scATAC-Seq analysis to over 8,000 human immunophenotypic blood cells from foetal liver and bone marrow. We inferred their differentiation trajectory and identified three highly proliferative oligopotent progenitor populations downstream from haematopoietic stem cell/multipotent progenitors (HS...

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Literature Corpus work: e1621b59-a424-5a88-a989-408ed578a6f1
DOI: 10.1101/2020.05.06.080259

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