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Article

A Unique Epigenomic Landscape Defines Human Erythropoiesis

1 Sept 2019

Abstract excerpt

Mammalian erythropoiesis yields a highly specialized cell type, the mature erythrocyte, evolved to meet the organismal needs of increased oxygen-carrying capacity. To better understand the regulation of erythropoiesis, we performed genome-wide studies of chromatin accessibility, DNA methylation, and transcriptomics using a recently developed strategy to obtain highly purified populations of primary human...

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Share to Epigenetics and DNA Methylation
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PMID: 31509757
DOI: 10.1016/j.celrep.2019.08.020

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