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Article

Global gene expression analysis of human erythroid progenitors

27 Jan 2011

Abstract excerpt

Understanding the pattern of gene expression during erythropoiesis is crucial for a synthesis of erythroid developmental biology. Here, we isolated 4 distinct populations at successive erythropoietin-dependent stages of erythropoiesis, including the terminal, pyknotic stage. The transcriptome was determined using Affymetrix arrays. First, we demonstrated the importance of using defined cell populations to...

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PMID: 21270440
DOI: 10.1182/blood-2010-07-290825

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