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MethPanel: a parallel pipeline and interactive analysis tool for multiplex bisulphite PCR sequencing to assess DNA methylation biomarker panels for disease detection

2020-02-10

Abstract excerpt

<h4>Background</h4> Multiplex bisulphite PCR sequencing is a convenient and scalable method to comprehensively profile DNA methylation at selected loci. The method is useful for validation of methylation biomarker panels on large clinical cohorts, as it can be applied to DNA isolated from fresh tissue, archival formalin fixed paraffin embedded tissue (FFPET) or circulating cell free DNA in plasma. However, succes...

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Literature Corpus work
33ebe30a-c070-5aeb-a35e-48b7dc5a53d8
DOI
10.1101/2020.02.09.941013
Open publication

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MethPanel: a parallel pipeline and interactive analysis tool for multiplex bisulphite PCR sequencing to assess DNA methylation biomarker panels for disease detectionDOI 10.1101/2020.02.09.941013
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