Article

Pipeline Olympics: continuable benchmarking of computational workflows for DNA methylation sequencing data against an experimental gold standard

2024-09-19

Abstract excerpt

DNA methylation is a widely studied epigenetic mark and a powerful biomarker of cell type, age, environmental exposures, and disease. Whole-genome sequencing following selective conversion of unmethylated cytosines into thymines via bisulfite treatment or enzymatic methods remains the reference method for DNA methylation profiling genome-wide. While numerous software tools facilitate processing of DNA methylation...

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Literature Corpus work: 3b53170d-d99d-5d82-a66d-f827ea0ba3c7
DOI: 10.1101/2024.09.16.609142

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