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Article

MethGo: a comprehensive tool for analyzing whole-genome bisulfite sequencing data.

BMC genomics - 1 Jan 2015

Liao Wen-Wei, Yen Ming-Ren, Ju Evaline, Hsu Fei-Man, Lam Larry, Chen Pao-Yang

Abstract excerpt

BACKGROUND: DNA methylation is a major epigenetic modification regulating several biological processes. A standard approach to measure DNA methylation is bisulfite sequencing (BS-Seq). BS-Seq couples bisulfite conversion of DNA with next-generation sequencing to profile genome-wide DNA methylation at single base resolution. The analysis of BS-Seq data involves the use of customized aligners for mapping bisulfite...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26680022
DOI: 10.1186/1471-2164-16-S12-S11
PMCID: PMC4682368

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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