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The diploid reference genome of a human embryonic stem cell line

2026-03-30

Abstract excerpt

<h4>ABSTRACT</h4> Advances in DNA sequencing and assembly technologies are spurring a shift from haploid reference genomes to sample-specific diploid assemblies. Here, we generated the first telomere-to-telomere (T2T) diploid reference for the widely used human embryonic stem cell (hESC) line, H9 (WAe009-A). This haplotype-resolved assembly is highly accurate with comprehensive annotation of genes, segmental dupl...

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Identifiers and source

Literature Corpus work
89fdf19b-bc00-52fa-acc5-60c7e74441f4
DOI
10.64898/2026.03.26.714432
Open publication

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