Article

Neuronal CBP-1 is required for enhanced body muscle proteostasis in response to reduced translation downstream of mTOR

2024-03-17

Abstract excerpt

<h4>Background</h4> The ability to maintain muscle function decreases with age and loss of proteostatic function. Diet, drugs, and genetic interventions that restrict nutrients or nutrient signaling help preserve long-term muscle function and slow age-related decline. Previously, it was shown that attenuating protein synthesis downstream of the mechanistic target of rapamycin (mTOR) gradually increases expression...

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Literature Corpus work: 33e33842-eb4b-5aa2-b490-07303a1c1ada
DOI: 10.1101/2024.03.15.585263

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