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Roles of progranulin and FRamides in neural versus non-neural tissues on dietary restriction-related longevity and proteostasis in <i>C. elegans</i>

2024-02-08

Abstract excerpt

Dietary restriction (DR) mitigates loss of proteostasis associated with aging that underlies neurodegenerative conditions including Alzheimer’s disease and related dementias. Previously, we observed increased translational efficiency of certain FMRFamide-like neuropeptide ( flp ) genes and the neuroprotective growth factor progranulin gene prgn-1 under dietary restriction in C. elegans . Here, we tested the eff...

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Literature Corpus work
3e0dedd7-1101-5b50-8f68-f5e2468f0179
DOI
10.1101/2024.02.06.579250
Open publication

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Roles of progranulin and FRamides in neural versus non-neural tissues on dietary restriction-related longevity and proteostasis in <i>C. elegans</i>DOI 10.1101/2024.02.06.579250
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