Article
Roles of progranulin and FRamides in neural versus non-neural tissues on dietary restriction-related longevity and proteostasis in <i>C. elegans</i>
2024-02-08
Abstract excerpt
Dietary restriction (DR) mitigates loss of proteostasis associated with aging that underlies neurodegenerative conditions including Alzheimer’s disease and related dementias. Previously, we observed increased translational efficiency of certain FMRFamide-like neuropeptide ( flp ) genes and the neuroprotective growth factor progranulin gene prgn-1 under dietary restriction in C. elegans . Here, we tested the eff...
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Identifiers and source
- Literature Corpus work
- 3e0dedd7-1101-5b50-8f68-f5e2468f0179
- DOI
- 10.1101/2024.02.06.579250
