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Article

Cellular Proteomes Drive Tissue-Specific Regulation of the Heat Shock Response.

G3 (Bethesda, Md.) - 10 Mar 2017

Ma Jian, Grant Christopher E, Plagens Rosemary N, Barrett Lindsey N, Kim Guisbert Karen S, Guisbert Eric

Abstract excerpt

The heat shock response (HSR) is a cellular stress response that senses protein misfolding and restores protein folding homeostasis, or proteostasis. We previously identified an HSR regulatory network in Caenorhabditis elegans consisting of highly conserved genes that have important cellular roles in maintaining proteostasis. Unexpectedly, the effects of these genes on the HSR are distinctly tissue-specific....

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Identifiers

PMID: 28143946
DOI: 10.1534/g3.116.038232
PMCID: PMC5345702

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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