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A New aspect of the pathology of brain tuberculosis: <i>Mycobacterium tuberculosis</i> infects and alters human neural progenitor cells

2026-08-20

Abstract excerpt

Brain tuberculosis remains associated with high mortality, and many survivors exhibit cognitive impairments. Progress in understanding the disease is hindered by the lack of human models. In this study, human neural organoids were infected, revealing that a subpopulation of neural progenitor cells (NPCs) is directly infected by apoptotic cell receptors expressed by NPCs, mediating bacterial uptake. Phagocytosed ba...

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Literature Corpus work
329e6077-5fd3-56ce-bf54-e5ed2ceafa1d
DOI
10.64898/2026.08.16.745136
Open publication

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A New aspect of the pathology of brain tuberculosis: <i>Mycobacterium tuberculosis</i> infects and alters human neural progenitor cellsDOI 10.64898/2026.08.16.745136
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