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Article

Immunoevasion and immunosuppression of the macrophage by <i><scp>M</scp>ycobacterium tuberculosis</i>

20 Feb 2015

Abstract excerpt

By virtue of their position at the crossroads between the innate and adaptive immune response, macrophages play an essential role in the control of bacterial infections. Paradoxically, macrophages serve as the natural habitat to Mycobacterium tuberculosis (Mtb). Mtb subverts the macrophage's mechanisms of intracellular killing and antigen presentation, leading ultimately to the development of tuberculosis (TB)...

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Identifiers

PMID: 25703562
DOI: 10.1111/imr.12268

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