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Article

Langhans giant cells from <i>M. tuberculosis</i>‐induced human granulomas cannot mediate mycobacterial uptake

17 Nov 2006

Abstract excerpt

Tuberculosis is characterized by a tight interplay between Mycobacterium tuberculosis (M. tb) and host cells within granulomas. These cellular aggregates restrain M. tb spreading but do not kill all bacilli, which persist for years. A more detailed investigation of the interaction between M. tb and granuloma cells is needed to improve our understanding of this persistence and to explain the physiopathology of...

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PMID: 17115379
DOI: 10.1002/path.2092

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