Article
Beyond macrophages: the diversity of mononuclear cells in tuberculosis.
Immunological reviews - 1 Nov 2014
Srivastava Smita, Ernst Joel D, Desvignes Ludovic
Abstract excerpt
Mycobacterium tuberculosis, the bacterium that causes tuberculosis (TB), is an intracellular pathogen of mononuclear phagocytes. Although M. tuberculosis has traditionally been thought to survive and replicate in macrophages, recent work in our laboratory and others has revealed that M. tuberculosis infects multiple subsets of mononuclear phagocytes in vivo and in vitro. In experimental animals, M. tuberculosis...
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