Article

A pluripotent stem cell atlas of multilineage differentiation reveals <i>TMEM88</i> as a developmental regulator of mammalian blood pressure

2022-10-14

Abstract excerpt

<h4>SUMMARY</h4> Pluripotent stem cells provide a scalable approach to analyse molecular regulation of cell differentiation across multiple developmental lineage trajectories. In this study, we engineered barcoded iPSCs to generate an atlas of multilineage differentiation from pluripotency, encompassing a time-course of WNT-induced differentiation perturbed using modulators of WNT, BMP, and VEGF signalling. Compu...

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Literature Corpus work: 3274ba61-0cf9-56bf-8bfa-a73dee06d576
DOI: 10.1101/2022.10.12.511862

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A pluripotent stem cell atlas of multilineage differentiation reveals <i>TMEM88</i> as a developmental regulator of mammalian blood pressureDOI 10.1101/2022.10.12.511862Read

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