Article

Single-cell RNA-seq of the Developing Cardiac Outflow Tract Reveals Convergent Development of the Vascular Smooth Muscle Cells at the Base of the Great Arteries

2018-11-13

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Rationale</h4> Cardiac outflow tract (OFT) is a major hotspot for congenital heart diseases (CHDs). A thorough understanding of the cellular diversity, transitions and regulatory networks of normal OFT development is essential to decipher the etiology of OFT malformations. <h4>Objective</h4> We sought to explore the cellular diversity and transitions between cell lineages during OFT develo...

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Literature Corpus work: 27709d17-640f-5298-8a83-719611be2f90
DOI: 10.1101/469346

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