Article
Variance component methods for analysis of complex phenotypes.
Cold Spring Harbor protocols - 1 May 2010
Almasy Laura, Blangero John
Abstract excerpt
Variance component methods have a long history in human quantitative genetics as well as in agricultural genetics and animal breeding. They are designed for genetic analysis of continuously varying quantitative traits such as body mass index (BMI), cholesterol levels, or intelligence quotient. They can be used to assess the strength of genetic effects on a trait, to localize genes influencing a trait through...
Topics
- Analysis of Variance
- Animals
- Genetic Linkage
- Humans
- Phenotype
- Plants
- Quantitative Trait, Heritable
