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Article

Testing for genetic associations in arbitrarily structured populations.

Nature genetics - 1 May 2015

Song Minsun, Hao Wei, Storey John D

Abstract excerpt

We present a new statistical test of association between a trait and genetic markers, which we theoretically and practically prove to be robust to arbitrarily complex population structure. The statistical test involves a set of parameters that can be directly estimated from large-scale genotyping data, such as those measured in genome-wide association studies (GWAS). We also derive a new set of methodologies,...

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PMID: 25822090
DOI: 10.1038/ng.3244
PMCID: PMC4464830

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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