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Article

HisCoM-G×E: Hierarchical Structural Component Analysis of Gene-Based Gene-Environment Interactions.

International journal of molecular sciences - 14 Sept 2020

Choi Sungkyoung, Lee Sungyoung, Huh Iksoo, Hwang Heungsun, Park Taesung

Abstract excerpt

Gene-environment interaction (G×E) studies are one of the most important solutions for understanding the "missing heritability" problem in genome-wide association studies (GWAS). Although many statistical methods have been proposed for detecting and identifying G×E, most employ single nucleotide polymorphism (SNP)-level analysis. In this study, we propose a new statistical method, Hierarchical structural...

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Identifiers

PMID: 32937825
DOI: 10.3390/ijms21186724
PMCID: PMC7555026

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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