Article
Variance components for statistical genetics: applications in medical research to characteristics related to human diseases and health.
Statistical methods in medical research - 1 Jan 1993
Hopper J L
Abstract excerpt
RA Fisher introduced variance components in 1918. He synthesized Mendelian inheritance with Darwin's theory of evolution by showing that the genetic variance of a continuous trait could be decomposed into additive and non-additive components. The model can be extended to include environmental factors, interactions, covariation, and non-random mating. Identifiability depends critically on design. Methods of...
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