Article

Induction of interferon signaling and allograft inflammatory factor 1 in macrophages in a mouse model of breast cancer metastases

2021-06-23

Abstract excerpt

<h4>Background: </h4> Metastatic breast cancer cells recruit macrophages (metastasis-associated macrophages, or MAMs) to facilitate their seeding, survival and outgrowth. However, a comprehensive understanding of the gene expression program in MAMs and how this program contributes to metastasis remain elusive. <h4>Methods: </h4>: We compared the transcriptomes of MAMs recruited to lung metastases and resident alv...

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Literature Corpus work: 326378d4-820e-5dcc-b387-5d4adbccc596
DOI: 10.12688/wellcomeopenres.16569.2

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