Article

tRNA 2’-O-methylation modulates small RNA silencing and life span in <i>Drosophila</i>

2019-07-11

Abstract excerpt

2’-O-methylation (Nm) represents one of the most common RNA modifications. Nm affects RNA structure and function with crucial roles in various RNA-mediated processes ranging from RNA silencing, translation, self versus non-self recognition to viral defense mechanisms. Here, we identify two novel Nm methyltransferases (Nm-MTases) in Drosophila melanogaster (CG7009 and CG5220) as functional orthologs of yeast TRM7...

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Identifiers and source

Literature Corpus work: 325c0037-81b5-5a57-b1fb-cb5e54b16cb5
DOI: 10.1101/699934

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