Article
Deep sequencing from hen1 mutants to identify small RNA 3' modifications.
Cold Spring Harbor symposia on quantitative biology - 1 Jan 2012
Zhai J, Meyers B C
Abstract excerpt
microRNAs (miRNAs) function via targeting of messenger RNAs, suppressing protein levels, and playing important roles in biological processes of plants and animals. The pathway for miRNA biogenesis is well established, but less is known about miRNA turnover, largely because of difficulties in capturing miRNAs during the process of decay, in which they are both rare and ephemeral. The HEN1 protein methylates the 3'...
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