Article
tRNA fragments (tRFs) populations analysis in mutants affecting tRNAs processing and tRNA methylation
2019-12-10
Abstract excerpt
tRNA fragments (tRFs) are a class of small non-coding RNAs (sncRNAs) derived from tRNAs. tRFs are highly abundant in many cell types including stem cells and cancer cells, and are found in all domains of life. Beyond translation control, tRFs have several functions ranging from transposon silencing to cell proliferation control. However, the analysis of tRFs presents specific challenges and their biogenesis is not...
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Identifiers and source
- Literature Corpus work
- 0e0debcd-282f-546a-93f9-1f489d51c705
- DOI
- 10.1101/869891