Article

ExtRamp Online: Enabling ramp sequence calculations via an intuitive web interface.

2021-09-16

Abstract excerpt

Motivation: Ramp sequences are an understudied evolutionarily-conserved mechanism for regulating protein translational efficiency. Slowly-translated codons concentrated at the 5' end of genes form ramp sequences that counterintuitively increase overall translational efficiency by evenly spacing ribosomes at initiation, which limits downstream ribosomal collisions. We previously developed ExtRamp, which is the only...

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Identifiers and source

Literature Corpus work: 32343c06-7dd3-56eb-bdfe-f1da583cb44c
DOI: 10.21203/rs.3.rs-908954/v1

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