Article

Structural basis of odorant recognition by a human odorant receptor

2022-12-20

Abstract excerpt

Our sense of smell enables us to navigate a vast space of chemically diverse odor molecules. This task is accomplished by the combinatorial activation of approximately 400 olfactory G protein-coupled receptors (GPCRs) encoded in the human genome 1–3 . How odorants are recognized by olfactory receptors (ORs) remains mysterious. Here we provide mechanistic insight into how an odorant binds a human olfactory recepto...

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Literature Corpus work: 321a1041-a00a-5bff-ad9e-874cca0f64c3
DOI: 10.1101/2022.12.20.520951

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