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Article

A single lysyl residue defines the binding specificity of a human odorant-binding protein for aldehydes.

FEBS letters - 3 Apr 2006

Tcatchoff Lionel, Nespoulous Claude, Pernollet Jean-Claude, Briand Loïc

Abstract excerpt

Odorant-binding proteins (OBPs) are small abundant soluble proteins belonging to the lipocalin superfamily, which are thought to carry hydrophobic odorants through aqueous mucus towards olfactory receptors. Human variant hOBP-2A has been demonstrated to bind numerous odorants of different chemical classes with a higher affinity for aldehydes and fatty acids. Three lysyl residues of the binding pocket (Lys62,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16546182
DOI: 10.1016/j.febslet.2006.03.017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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