Article

Cardiac myofibril networks induce shear stress

2025-11-12

Abstract excerpt

Myofibril arrangement is critical to cardiac muscle function in health and disease. Historically, analysis of the impact of myofibril organisation on force and cell contraction has relied on the assumption of uniaxial arrays. However, improvements in imaging indicate that myofibrils form complex networks, though how these networks modulate force has yet to be explored. Here, morphological analysis of sheep left-ve...

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Literature Corpus work: 3210f9d0-7809-54b3-aa27-3aada5dc8722
DOI: 10.1101/2025.11.10.687713

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