Article

Independent regulation of Z-lines and M-lines during sarcomere assembly in cardiac myocytes revealed by the automatic image analysis software sarcApp

2023-01-12

Abstract excerpt

<h4>ABSTRACT</h4> Sarcomeres are the basic contractile units within cardiac myocytes, and the collective shortening of sarcomeres aligned along myofibrils generates the force driving the heartbeat. The alignment of the individual sarcomeres is important for proper force generation, and misaligned sarcomeres are associated with diseases including cardiomyopathies and COVID-19. The actin bundling protein, α-actinin...

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Literature Corpus work: 0a99b047-5441-5d23-9ee7-f9ad1b27aa07
DOI: 10.1101/2023.01.11.523681

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