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Article

Monitoring the maturation of the sarcomere network: a super-resolution microscopy-based approach.

Cellular and molecular life sciences : CMLS - 23 Feb 2022

Skorska Anna, Johann Lisa, Chabanovska Oleksandra, Vasudevan Praveen, Kussauer Sophie, Hillemanns Maximilian, Wolfien Markus, Jonitz-Heincke Anika, Wolkenhauer Olaf, Bader Rainer, Lang Hermann, David Robert, Lemcke Heiko

Abstract excerpt

The in vitro generation of human cardiomyocytes derived from induced pluripotent stem cells (iPSC) is of great importance for cardiac disease modeling, drug-testing applications and for regenerative medicine. Despite the development of various cultivation strategies, a sufficiently high degree of maturation is still a decisive limiting factor for the successful application of these cardiac cells. The maturation...

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Identifiers

PMID: 35199227
DOI: 10.1007/s00018-022-04196-3
PMCID: PMC8866374

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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