Article

Unravelling the transcriptome of the human tuberculosis lesion and its clinical implications

2022-04-03

Abstract excerpt

<h4>ABSTRACT</h4> The granuloma is a complex structure, contributing to the overall spectrum of tuberculosis (TB). We characterised 44 fresh human pulmonary TB lesion samples from 13 patients (drug-sensitive and multi-drug resistant TB) undergoing therapeutic surgery using RNA-Sequencing. We confirmed a clear separation between the granuloma and adjacent non-lesional tissue, with the granuloma samples consistently...

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Literature Corpus work: 63ba3173-55aa-5948-ad84-18b1b9b41617
DOI: 10.1101/2022.03.31.22273171

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