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Chronic Stress Disrupts the Homeostasis and Progeny Progression of Oligodendroglial Lineage Cells, Associating Immune Oligodendrocytes With Prefrontal Cortex Hypomyelination

2022-03-14

Abstract excerpt

<title>Abstract</title> <p>Major Depressive Disorder (MDD) is a chronic debilitating illness affecting yearly 300 million people worldwide. Oligodendrocyte-lineage cells have emerged as important neuromodulators in synaptic plasticity and crucial components of MDD pathophysiology. Using the repeated social defeat (RSDS) mouse model, we demonstrate that chronic psychosocial stress induces long-lasting losses and t...

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Literature Corpus work
31b6e53c-a889-55ed-b128-deaea8d03f2b
DOI
10.21203/rs.3.rs-882180/v1
Open publication

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Chronic Stress Disrupts the Homeostasis and Progeny Progression of Oligodendroglial Lineage Cells, Associating Immune Oligodendrocytes With Prefrontal Cortex HypomyelinationDOI 10.21203/rs.3.rs-882180/v1
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