Article

A meta-analysis of the effects of early life stress on the prefrontal cortex transcriptome suggests long-term effects on myelin

2024-11-24

Abstract excerpt

<h4>Background</h4> Early life stress (ELS) refers to exposure to negative childhood experiences, such as neglect, disaster, and physical, mental, or emotional abuse. ELS can permanently alter the brain, leading to cognitive impairment, increased sensitivity to future stressors, and mental health risks. The prefrontal cortex (PFC) is a key brain region implicated in the effects of ELS. <h4>Methods</h4> To better...

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Literature Corpus work: d73a756e-147f-5342-82ca-5199dff360d4
DOI: 10.1101/2024.11.22.624315

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