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Article

Genetic Control of Myelin Plasticity after Chronic Psychosocial Stress

1 Jul 2018

Abstract excerpt

Anxiety disorders often manifest in genetically susceptible individuals after psychosocial stress, but the mechanisms underlying these gene-environment interactions are largely unknown. We used the chronic social defeat stress (CSDS) mouse model to study resilience and susceptibility to chronic psychosocial stress. We identified a strong genetic background effect in CSDS-induced social avoidance (SA) using four...

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PMID: 30073192
DOI: 10.1523/eneuro.0166-18.2018

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