Article

Cell-resolved cortical architecture and intercellular communication distinguish bipolar and major depressive disorders

2026-07-27

Abstract excerpt

<title>Abstract</title> <p>Bipolar disorder (BD) and major depressive disorder (MDD) overlap clinically, particularly during depressive episodes, yet diverge in longitudinal course, treatment response, and underlying neurobiology. Whether this overlap reflects graded disruption along a shared depressive axis or distinct cortical organization remains unclear, underscoring the need to distinguish shared from disord...

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Literature Corpus work: f285de11-902c-5f58-941f-28f40d348588
DOI: 10.21203/rs.3.rs-10395576/v1

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