Article

Systematic genetic mapping of necroptosis identifies SLC39A7 as modulator of death receptor trafficking

2018-03-29

Abstract excerpt

<h4>ABSTRACT</h4> Regulation of cell and tissue homeostasis by programmed cell death is a fundamental process with wide physiological and pathological implications. The advent of scalable somatic cell genetic technologies creates the opportunity to functionally map these essential pathways, thereby identifying potential disease-relevant components. We investigated the genetic basis underlying necroptotic cell dea...

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Literature Corpus work: 317de681-7fd5-5616-ba0c-017ec2202392
DOI: 10.1101/290718

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