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Article

The genetic interaction map of the human solute carrier superfamily

2024-10-09

Abstract excerpt

Solute carriers (SLCs), the largest superfamily of transporter proteins in humans with about 450 members, control the movement of molecules across membranes. A typical human cell expresses over 200 different SLCs, yet their collective influence on cell phenotypes is not well understood due to overlapping substrate specificities and expression patterns. To address this, we performed systematic pairwise gene double...

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Literature Corpus work
7f03db2a-081a-553e-ac5b-12316d0455a4
DOI
10.1101/2024.10.07.616442
Open publication

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The genetic interaction map of the human solute carrier superfamilyDOI 10.1101/2024.10.07.616442
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