Article

An ATF4-centric regulatory network is required for the assembly and function of the OXPHOS system

2023-09-21

Abstract excerpt

<h4>ABSTRACT</h4> Identifying the factors that determine mammalian cell viability when oxidative phosphorylation (OXPHOS) function is impaired poses challenges due to the diverse cellular responses and limited clinical material availability. Moreover, animal models often fail to replicate human phenotypes. To address these challenges, this study conducted comprehensive analyses involving multiple defects and spec...

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Literature Corpus work: 30b3af7c-28ae-5c1f-a6a4-466b3ed594b9
DOI: 10.1101/2023.09.21.558853

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