Article

Endothelial Slit2 guides the Robo1-positive sympathetic innervation during heart development

2025-01-22

Abstract excerpt

Axon guidance cues direct nerves in the heart during development, disease and regeneration. These cues determine cardiac innervation patterning by regulating the balance between chemo-attraction and chemo-repulsion. However, the role of one of the most crucial ligand-receptor combinations among axon guidance molecules, the Slit chemo-active ligands and their Roundabout (Robo) transmembrane receptors, remains unkno...

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Literature Corpus work: 304e77a6-6032-56f6-b12e-830029613f0b
DOI: 10.1101/2025.01.22.634222

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