A neuro-lymphatic communication guides lymphatic development by CXCL12 and CXCR4 signaling

Abstract excerpt

Lymphatic vessels grow through active sprouting and mature into a vascular complex that includes lymphatic capillaries and collecting vessels that ensure fluid transport. However, the signaling cues that direct lymphatic sprouting and patterning remain unclear. In this study, we demonstrate that chemokine signaling, specifically through CXCL12 and CXCR4, plays crucial roles in regulating lymphatic development. We...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Lymphatic System and Diseases
• Share to Planarian Biology and Electrostimulation
• Share to Sympathectomy and Hyperhidrosis Treatments