Article

The proton-sensing GPR4 receptor regulates paracellular gap formation and permeability of vascular endothelial cells

2019-04-06

Abstract excerpt

Tissue acidosis can be a consequence of numerous disease states including stroke, myocardial infarction, limb ischemia, and inflammation. Blood vessels existing in the affected tissues are associated with the progression of acidosis-related diseases. However, the mechanisms by which endothelial cells (ECs) lining the affected blood vessels sense and respond to an acidic microenvironment remain largely unclear. We...

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Literature Corpus work: 300f52e2-9b25-5e04-a511-ef4c67ec1cb7
DOI: 10.1101/601088

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