Article

Discovery of 10,828 new putative human immunoglobulin heavy chain IGHV variants

2021-01-17

Abstract excerpt

The correct identification of immunoglobulin alleles in genome sequences is a challenge. Nevertheless, it can assist in the study of several human diseases associated with the antibody repertoire and in the development of new therapies using antibody engineering techniques. The advent of next-generation sequencing of human genomes and antibody repertoires enabled the development of several tools for the mapping an...

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Literature Corpus work: 2fe8c0f1-54a1-581a-8f6f-0f90b802a012
DOI: 10.1101/2021.01.15.426262

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