Article

Selective Translation Complex Profiling Reveals Staged Initiation and Co-translational Assembly of Initiation Factor Complexes

2019-10-16

Abstract excerpt

<h4>SUMMARY</h4> Translational control targeting mainly the initiation phase is central to the regulation of gene expression. Understanding all of its aspects requires substantial technological advancements. Here we modified yeast Translational Complex Profile sequencing (TCP-seq), related to ribosome profiling, and adopted it for mammalian cells. Human TCP-seq, capable of capturing footprints of 40S subunits (40...

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Literature Corpus work: 2fcd5679-0f67-5748-a5dc-9e81efe0770c
DOI: 10.1101/806125

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