Article
Human IRES Atlas: an integrative platform for studying IRES-driven translational regulation in humans
1 Jan 2021
Abstract excerpt
It is now known that cap-independent translation initiation facilitated by internal ribosome entry sites (IRESs) is vital in selective cellular protein synthesis under stress and different physiological conditions. However, three problems make it hard to understand transcriptome-wide cellular IRES-mediated translation initiation mechanisms: (i) complex interplay between IRESs and other translation...
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