Article

High-Throughput Translational Profiling with riboPLATE-seq

2019-10-25

Abstract excerpt

<h4>ABSTRACT</h4> Protein synthesis is dysregulated in many diseases, but we lack a systems-level picture of how signaling molecules and RNA binding proteins interact with the translational machinery, largely due to technological limitations. Here we present riboPLATE-seq, a scalable method for generating paired libraries of ribosome-associated and total mRNA. As an extension of the PLATE-seq protocol, riboPLATE-...

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Literature Corpus work: 7af181a1-9430-5880-a18e-30762f3e953f
DOI: 10.1101/819094

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