Article

Synergistic Control of Mitochondrial Dynamics and Function by ERAD and Autophagy in Brown Adipocytes

2025-06-15

Abstract excerpt

<h4>ABSTRACT</h4> Mitochondrial quality control is essential for maintaining cellular energy homeostasis, particularly in brown adipocytes where dynamic mitochondrial remodeling supports thermogenesis. Although the SEL1L-HRD1 endoplasmic reticulum (ER)-associated degradation (ERAD) pathway and autophagy are two major proteostatic systems, how these pathways intersect to regulate mitochondrial integrity in metabol...

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Literature Corpus work: 2fc3c3ca-8578-57dc-9ab9-aef16c234958
DOI: 10.1101/2025.06.14.659625

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