Article

Early changes of ER-mitochondrial interaction in the liver of high-fat diet-fed mice

2026-04-14

Abstract excerpt

<h4>ABSTRACT</h4> IP3R-Grp75-VDAC1 protein complex at the mitochondria-ER contact sites (MERCS) is involved in response to nutrients and control of glucose and energy metabolism, however, early alterations of the complex and MERCS in response to increased fat intake remain inconclusive. We investigated early effects of high-fat diet (HFD) on IP3R-Grp75-VDAC1 protein expression in correlation with ER-mitochondrial...

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Literature Corpus work: 94c6cf78-9ed9-578a-8e98-e0b7c2716a7b
DOI: 10.64898/2026.04.11.717879

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