Article

ESYT1 tethers the endoplasmic reticulum to mitochondria and is required for mitochondrial lipid and calcium homeostasis

2022-11-15

Abstract excerpt

<h4>SUMMARY</h4> Mitochondria interact with the endoplasmic reticulum (ER) at structurally and functionally specialized membrane contact sites known as mitochondria-ER contact sites (MERCs). MERCs are crucial for a myriad of physiological functions including lipid synthesis and transport, and calcium signaling. Alterations in the structure, composition or regulation of MERCs contribute to the aetiology of many pa...

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Literature Corpus work: e03b3c66-66f2-5fd5-96a2-4b342217ae85
DOI: 10.1101/2022.11.14.516495

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