Article

The meta-epigenomic structure of purified human stem cell populations is defined at <i>cis</i> -regulatory sequences

2014-08-01

Abstract excerpt

<h4>ABSTRACT</h4> The mechanism and significance of epigenetic variability in the same cell type between healthy individuals are not clear. Here, we purify human CD34+ hematopoietic stem and progenitor cells (HSPCs) from different individuals and find that there is increased variability of DNA methylation at loci with properties of promoters and enhancers. The variability is especially enriched at candidate enhan...

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Literature Corpus work: 9bc5ec75-cf6f-5c4c-bb6c-927280e187bc
DOI: 10.1101/007591

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