Article

Global network structure and local transcriptomic vulnerability shape atrophy in sporadic and genetic behavioral variant frontotemporal dementia

2021-08-26

Abstract excerpt

Connections among brain regions allow pathological perturbations to spread from a single source region to multiple regions. Patterns of neurodegeneration in multiple diseases, including behavioral variant of frontotemporal dementia (bvFTD), resemble the large-scale functional systems, but how bvFTD-related atrophy patterns relate to structural network organization remains unknown. Here we investigate whether neuro...

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Literature Corpus work: 2f9f33e5-71fc-5fd7-aaf0-ea3005e28309
DOI: 10.1101/2021.08.24.457538

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